PICO is not the best choice for all research questions. Here are a few examples of other question frameworks.
ECLIPSE- Health Policy or Management questions
E- Expectation - Why is the information needed?
C- Client Group - Who needs or will use the information?
L- Location - Where is the service taking place?
I- Impact - What is being evaluated? How will success be measured?
P- Professionals - Who provides the service?
S- Service - What is the service being evaluated?
Research question: How can I increase access to reliable health information to patients with newly diagnosed diabetes?
SPIDER- Qualitative questions
S- Sample- Who is being studied?
PI- Phenomenon of Interest- What reasons drive the behavior or experience?
D- Study Design- How was the study designed and conducted?
E- Evaluation- What is the outcome and how is it measured?
R- Research Type- What type of research is it?
Research Question: What is the experience of teenagers wearing a continuous glucose monitor?
Booth, A., Noyes, J., Flemming, K., Moore, G., Tunçalp, Ö., & Shakibazadeh, E. (2019). Formulating questions to explore complex interventions within qualitative evidence synthesis. BMJ global health, 4(Suppl 1), e001107. https://doi.org/10.1136/bmjgh-2018-001107